Ageing rarely shows up as one isolated problem. Over time, skin can become drier, duller, less bouncy and less resilient, while fine lines become more noticeable. At the same time, UV exposure, pollution, climate and even overuse of strong skincare can add to the stress your skin is already dealing with. BioRegenesis was created to address that bigger picture of overall skin quality, rather than chasing one wrinkle at a time.

That is why the formula is built around three jobs: Repair. Protect. Rebuild.

Repair: 3% Salmon PDRN works alongside 0.5% Polyglutamic Acid, Panthenol and other humectants to support skin renewal, barrier recovery and hydration — helping stressed, dehydrated skin feel more comfortable, plump and resilient.

Protect: 1% Ectoin and a five-species Marine Seaweed Complex help support skin against pollution, UV-induced stress and everyday environmental exposure — factors that can contribute to premature visible ageing over time.

Rebuild: 2% Matrixyl Synthé’6 and 2% GABA target the visible changes that come with ageing, helping improve the look of firmness, bounce, smoothness, fine lines and expression lines.

Bringing all three together is what makes BioRegenesis different from a basic hydration serum, a simple barrier serum or a formula built around PDRN alone. The six-active system is designed to support skin on multiple fronts at once — hydration and recovery now, with firmness, resilience and overall skin quality supported over time.

It is also retinol-free and gentle enough for daily AM and/or PM use. You can use it as your entry into preventative ageing if you are not ready for Retinol, or alongside an existing Retinol routine for complementary PDRN, peptide, hydration and environmental support. It is clinic-inspired daily skincare, but not a replacement for injectable PDRN treatments.

Apply 3–4 drops to clean, slightly damp skin, morning and/or night, then follow with moisturiser. In the morning, finish with sunscreen.

If your skin is sensitive or over-treated, start once daily for the first week, then increase to twice daily if comfortable. BioRegenesis can also be used alongside stronger actives. It is especially effective when used alongside our Encapsulated Retinol + B5 Serum for targeting the early signs of skin ageing.

3% Stabilized Salmon PDRN
A salmon-derived DNA fragment used in the same ingredient category as professional PDRN skin-booster treatments. In BioRegenesis, it supports skin renewal, barrier recovery and overall resilience as part of a daily topical routine.

2% Matrixyl Synthé’6
A peptide designed to support the skin’s structural matrix, helping improve the look of firmness, smoothness and fine lines over time. It is one of the key ingredients behind the serum’s Rebuild pillar.

1% Ectoin
An extremolyte that helps skin cope with environmental stress, including pollution, heat and UV-induced stress, while also supporting hydration. This makes it especially relevant for daily urban skincare.

2% GABA
Included to help soften the appearance of expression lines caused by repeated facial movement, while also supporting smoother-looking skin. It complements Matrixyl Synthé’6 by targeting a different aspect of visible ageing.

0.5% Polyglutamic Acid
A high-performance humectant that helps skin hold onto water, supporting a plumper, smoother and more hydrated appearance. It helps make the formula immediately rewarding while the longer-term age-defence benefits build over time.

Marine Seaweed Complex
A five-algae complex that provides antioxidant support, mineral-rich hydration and environmental defence. It strengthens the Protect pillar alongside Ectoin.

Panthenol
A supporting barrier and hydration ingredient that helps improve comfort, moisture retention and skin resilience, especially useful for skin that feels stressed or over-treated.

Aqua, Glycerin, DNA, Carbomer, Dimethyl Isosorbide, Aminobutyric Acid, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Ectoin, Laminaria Japonica Extract, Undaria Pinnatifida Extract, Sargassum Fusiforme Extract, Sargassum Fulvellum Extract, Enteromorpha Compressa Extract, 1,2-Hexanediol, Panthenol, Ethylhexylglycerin, Phenoxyethanol, Polyacrylate Crosspolymer-6, Sodium Polyglutamate.